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Opera Mundi to miss Aintree Grand National

Paul Nicholls´ Opera Mundi has been ruled out of the John Smith´s Grand National after suffering a setback.

Barry Simpson, racing manager for owner Sir Robert Ogden, said: "He´s got an infection which has caused swelling in a joint.

"We walked the horse last night and he´s been on the walker this morning just to see if it can be walked off - but unfortunately it can´t.

"We could have left it until tomorrow (Saturday) morning but there´s a reserve system in place and we want to play the game fairly."

Opera Mundi, the intended mount of Liam Heard, was a general 66-1 chance for Aintree glory.

Nigel Twiston-Davies´ Ardaghey, the first reserve for the National, has been promoted into the field, with David England booked to ride the nine-year-old.